Responsible dog breeding places high demands on breeders. Animal‑welfare–oriented and sustainable selection of breeding animals requires sound knowledge of genetics and hereditary diseases. A lack of knowledge regarding pregnancy, birth, and puppy development can jeopardize the health of the mother dog and her offspring. Collaboration between breeders, legislators, authorities, the veterinary profession, and dog owners is therefore essential. The guidelines support responsible breeding, a good start to a dog’s life, and obligate breeders to find suitable and responsible homes for their puppies.